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Multi-Purpose Solution
The GPA100 offers high performance, fully automated separation tools for protein analysis based on molecular size, shape, and charge. Our ready-to-run system is delivered to you with a comprehensive library of protein methods suitable for most applications and our applications department is ready to help you with your specific needs.
- This is the system:
- For early stage drug development through product QA;
- For unparalleled chromatographic resolution, sensitivity, and speed;
- For results that are reproducible and quantifiable; and
- Through its modular, open systems approach enables connection to all current and future detectors, CE-Mass Spec interfaces, and sample preparation devices.
- An Automated Solution - The Key to System Performance
- Built-in system automation relieves you and your team from the tedious and repetitive tasks associated with classic electrophoresis techniques resulting in:
- Improved efficiency,
- Enhanced productivity,
- Increased throughput,
- Greater accuracy, and
- Increased sampling frequency for improved process statistics and monitoring.
- Modular and Customizable Solutions
- The GPA100’s modular design allows broad flexibility in instrument configuration that:
- Is tailored to the exact needs of each application,
- Has a smaller footprint resulting in efficient and economical use of lab space, and
- Has components and methods chosen to suit every application.
Superior to Slab Gel Electrophoresis
Eliminate the labor-intensive three to four hour slab gel electrophoresis process. The GPA100 automated process generates data in 30 minutes per sample, 24 hours a day, 7 days a week. You can count on the GPA100 to reduce labor costs while performing timely and efficient assays around the clock.
- PLUS, you get the added benefit of the GPA100’s superior accuracy and precision.
- These benefits are valuable when:
- Tracking a rapidly-changing process,
- Optimizing process yields, or when
- Developing statistical databases.
- Superior to Protein HPLC
- If you currently perform protein HPLC then compare the GPA100 to your current method. When you use the GPA100 you will enjoy:
- Increased accuracy, precision, and automation;
- Dramatically decreased assay time;
- Dramatically lower operating costs;
- Reduced maintenance; and
- Familiar and powerful software systems.
- Hardware Components of the System
- Automated Injector – Patented, programmable injection system that generates highly accurate and reproducible sample injection quantities, resulting in better science.
- Autosampler and Fraction Collector – Allows the system to be configured to individual needs.
- Software Modules – Gives functional control for pressure, voltage, current, temperature, timed events, and detectors. Acquires data from all detectors and monitors system status. The software also allows you to program and save complete sets of method parameters. Complete data reduction, archiving, and reporting. Fully auditable.
- Full Control High Voltage Power Supply (HVPS) – Enables voltage or current profiles to be programmed and accurately controlled, and incorporates a fast polarity switching feature to deliver fast and efficient separations.
Warranty, Parts and Service
The GPA100 carries a full one-year warranty. Service Contracts are available for 24-hour, 48-hour, 5-day, or as-needed service at the customer’s site or at Groton’s facility.
Groton Biosystems stocks a comprehensive inventory of lamps, filters, reagents, and replacement parts for fast delivery to your facility.
GPA100 Features and Options
- The GPA100 is a highly automated Capillary Electrophoresis CEC System that features:
- A universal capillary combined with reagent systems that separates virtually all proteins of commercial interest;
- A broad selection of detectors;
- A simple and highly automated operation that can be calibrated accurately and automatically in minutes; and
- Cost-effective, accurate, and multi-purpose performance – without leaks, plumbing, and solvent consumption.
GPA100 Technical Specifications
- Capillary
- Variable in length and diameter depending on application / configuration.
- Injection Modes
- Hydrodynamic injection
- Electrokinetic injection - controlled voltage or current ramps
- Injection Pressure
- Variable from -180 to +250mbar with 1mbar resolution
- Voltage range
- 0 to +30kV or -30kV, 100 V increments
- Current range
- 0 to +200pA and -200pA, 1 uA increments, time-programmable
- Repeatability
- Better than 0.1% RSD (voltage, current)
- Programmable Ramp
- Voltage or current
- Voltage Ramp
- 0.1-50kV/s CE, resolution 100 V/s
- 0.01-50kV/s CEC, resolution 10 V/s
- Polarity Reversal
- Programmable during pre-run and run conditions
- Autosampler/Fraction Collector
- 30/48 position carrousel Vials randomly accessible from inlet and outlet end of the capillary
- All systems accept variable vial sizes for samples and buffers, including Eppendorf micro centrifuge tubes
- Temperature control
- Sample/Buffer tray 4 to 40 C
- Capillary 5 C below ambient to 60 C
- Injection duration:
- Max 650min, resolution 0,01 min
- Repeatability of Injected volume:
- < 1.0% RSD
- Power requirements:
- Mains voltage 115V or 230V Mains 50/60Hz 300VA
- Dimensions:
- Approximate Height 50cm (20 inch) x Depth 54cm (22 inch)
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Giangarlo Scientific Co, Inc. 2005
162 Steuben Street - Pittsburgh, PA 15220
1-800-229-8850 - (412) 922-8850 - (412) 922-9047 FAX
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